Thermo Fisher Scientific PDX1 Monoclonal Antibody (OTI7F7), TrueMAB
인간 PDX1 단백질을 타깃으로 하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol 버퍼에 보관됩니다. 인슐린 유전자 발현 및 췌장 발달 연구용으로 사용됩니다.
- 카탈로그번호
- TA807531
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F7 |
| Immunogen | Full length human recombinant protein of human PDX1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2.
This nuclear protein is involved in early pancreatic development and plays a major role in glucose-dependent regulation of insulin gene expression.
Defects in this gene can cause pancreatic agenesis, leading to early-onset insulin-dependent diabetes mellitus (NIDDM) and maturity onset diabetes of the young type 4 (MODY4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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