Thermo Fisher Scientific PTPRM Polyclonal Antibody
Thermo Fisher Scientific의 PTPRM Polyclonal Antibody는 인간 단백질에 반응하는 염소 유래 다클론 항체로, Western blot 및 IHC(P)에서 검증되었습니다. 두 가지 isoform을 인식하며, 세포 신호 조절 연구에 적합합니다. 연구용으로만 사용 가능합니다.
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- PA5142321
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KLIRQVDKWQEEYN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932972 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_001098714.1 and NP_002836.3).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules involved in regulating cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP includes:
- An extracellular region with MAM, Ig-like, and fibronectin type III-like domains
- A single transmembrane region
- Two tandem catalytic domains
It mediates cell-cell aggregation through homophilic interactions and can interact with scaffolding protein RACK1/GNB2L1, which may be essential for downstream signaling in response to cell adhesion.
Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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