Thermo Fisher Scientific PSMB7 Monoclonal Antibody (OTI4D12), TrueMAB
PSMB7 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot에 적합하며 Human 및 Mouse 시료에서 반응. 친화 크로마토그래피로 정제된 액상형 항체로, 안정적인 보관을 위해 -20°C에서 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 58–277 of human PSMB7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of four rings of 28 non-identical subunits. Two rings contain seven alpha subunits and two rings contain seven beta subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal process. The immunoproteasome, a modified form, processes class I MHC peptides.
The PSMB7 gene encodes a member of the proteasome B-type (T1B) family, a 20S core beta subunit. Its expression is downregulated by gamma interferon, and proteolytic processing is required for maturation. This subunit is absent in the immunoproteasome, where it is replaced by the beta 10 subunit (2i).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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