Thermo Fisher Scientific beta-2 Adrenergic Receptor VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1252)
Recombinant alpaca VHH monoclonal antibody recognizing human beta-2 adrenergic receptor. Suitable for Flow Cytometry, ELISA, and RIA. Produced in CHO cells, purified by metal-chelate chromatography, and supplied as liquid form in PBS without preservative.
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Applications
- Flow Cytometry (Flow): Assay-dependent
- ELISA (ELISA): Assay-dependent
- Radioimmune Assays (RIA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1252 |
| Immunogen | Recombinant Human ADRB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3).
ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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