Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI1D4), TrueMAB
C17orf37 단백질을 인식하는 Mouse monoclonal 항체로, Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 제품. PBS/BSA/glycerol buffer에 보관되며, -20°C에서 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D4 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.98 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
During the past decade, the role of the ERBB2 (neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established.
The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies.
The C35 gene is located on chromosome 17q12, 505 nucleotides from the 3' end of the ERBB2 oncogene, the antigenic target for trastuzumab (Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 and ERBB2 is tail to tail.
The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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