Thermo Fisher Scientific IGLL1 Polyclonal Antibody
IGLL1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human과 Mouse 시료에 반응하며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human IGLL1 (amino acids 151–213) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The preB cell receptor, CD179b, is expressed on the surface of proB and preB cells and plays a key role in signal transduction for cellular proliferation and differentiation from the proB to preB stage. It also contributes to allelic exclusion at the Ig heavy chain gene locus and promotes Ig light chain rearrangements.
This gene encodes one of the surrogate light chain subunits and belongs to the immunoglobulin gene superfamily. Mutations in this gene can cause B cell deficiency and agammaglobulinemia, an autosomal recessive disease characterized by the absence or severe reduction of gamma globulins or antibodies. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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