Thermo Fisher Scientific SFRS15 Polyclonal Antibody
Human 및 Mouse 반응성을 가지는 Rabbit Polyclonal SFRS15 항체. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific SFRS15 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SFRS15 (Product #RP-95879) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647191 |
Product Specific Information
Immunogen sequence:
KVKPEELESF CEGGMLDSDT LNPDWKGIPK KPENEVAQNG GAETSHTEPV SPIPKPLPVP VPPIPVPAPI TVPPPQVPPH QPGPPVVGAL QP
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 95%
Target Information
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites.
Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domain. SFRS15 interacts with the C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing.
Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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