Thermo Fisher Scientific ID3 Monoclonal Antibody (OTI10D3), TrueMAB
ID3 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC(P), Flow Cytometry 등 다양한 응용에 적합. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. -20°C에서 안정적 보관 가능.
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- TA500791x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ID3 Monoclonal Antibody (OTI10D3), TrueMAB
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D3 |
| Immunogen | Full length human recombinant protein of human ID3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3, and ID4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The ID-type proteins negatively regulate DNA binding of bHLH proteins.
ID1 inhibits DNA binding of E12 and Myo D, functioning to inhibit muscle-specific gene expression. During muscle cell differentiation, ID protein levels decrease, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, activating myogenic differentiation. Expression of ID proteins is strongly dependent on growth factor activation. Reduction of ID mRNA levels by antisense oligonucleotides delays reentry of arrested cells into the cell cycle following growth factor stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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