Thermo Fisher Scientific SNX8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SNX8. Recombinant protein control fragment (Product #RP-92668). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SNX8,uniProtId:Q9Y5X2-1,ncbiNodeId:9606,antigenRange:335-449,antigenLength:465,antigenImageFileName:PA5-63428_SNX8_Q9Y5X2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63428_SNX8_Q9Y5X2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647732

Product Specific Information

Immunogen sequence: EKGVLHKHQR ALHKYSLMKR QMMSATAQNR EPESVEQLES RIVEQENAIQ TMELRNYFSL YCLHQETQLI HVYLPLTSHI LRAFVNSQIQ GHKEMSKVWN DLRPKLSCLF AGPHS

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX8 is an ortholog of a yeast protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.