
Thermo Fisher Scientific Thrombomodulin Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
0.1 µg/mL
Immunocytochemistry (ICC/IF)
5-15 µg/mL
Flow Cytometry (Flow)
2.5 µg per million cells
Immunoprecipitation (IP)
25 µg/mL
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Thrombomodulin/BDCA-3 Leu17-Ser517 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Thrombomodulin (CD141),
uniProtId:
P15306-1,
ncbiNodeId:
10090,
antigenRange:
17-517,
antigenLength:
577,
antigenImageFileName:
PA5-47550_Thrombomodulin_CD141_P15306-1_Goat.svg,
antigenImageFileNamePDP:
PA5-47550_Thrombomodulin_CD141_P15306-1_Goat_PDP.jpeg,
sortOrder:
2}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609393
Product Specific Information
In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human Thrombomodulin is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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