Thermo Fisher Scientific PPP2R1B Monoclonal Antibody (OTI8C5), TrueMAB
PPP2R1B 단백질 인식용 단클론 항체로 Western blot에 적합. Human, Mouse, Rat 반응성. 동결건조 형태로 1 mg/mL 농도. PBS 완충액(8% trehalose) 포함, -20°C 보관. 연구용으로 단백질 탈인산화 조절 연구에 활용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–601 of human PPP2R1B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
In eukaryotes, phosphorylation and dephosphorylation of serine and threonine residues regulate diverse cellular processes such as division, homeostasis, and apoptosis. Protein phosphatases are key regulators in this mechanism. The protein phosphatase (PP) holoenzyme typically consists of a regulatory, variable, and catalytic subunit.
Major PP families include PP1, PP2A, PP2B (calcineurin), and PP2C, with PP4 (PPX) as an additional member. The PP2A family contains subunits PP2Aα and PP2Aβ, which associate with various regulatory subunits such as PP2A-Aα, -Aβ, PP2A-Bα, -Bβ, PP2A-Cα, -Cβ, and PP2A-B56α, -B56β.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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