Thermo Fisher Scientific ZC3H8 Monoclonal Antibody (OTI3G10), TrueMAB
인간 ZC3H8 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며, PBS 및 trehalose 완충액에 보관됩니다. 연구용으로만 사용되며, GATA3 유전자 조절 연구에 활용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G10 |
| Immunogen | Full length human recombinant protein of human ZC3H8 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) functions as a transcriptional repressor of the GATA3 promoter.
It binds specifically to the 5'-AGGTCTC-3' sequence within the intronic regulatory region (IRR) of the GATA3 gene.
Overexpression of ZC3H8 induces thymocyte apoptosis, suggesting its role in thymocyte homeostasis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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