Thermo Fisher Scientific KCNN2 Polyclonal Antibody
KCNN2 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능하며, Rabbit IgG 호스트로 제작되었습니다. 동결건조 형태로 제공되며 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:200–1:1,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | |
| Immunocytochemistry (ICC/IF) | 1:200 | |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)ETQMENYDKHVTYNAERS, corresponding to amino acid residues 542–559 of rat KCa2.2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736014 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and influence neuronal firing patterns. Each AHP component is kinetically distinct and mediated by different calcium-activated potassium channels.
The KCNN2 gene encodes a protein that regulates neuronal excitability by contributing to the slow component of synaptic AHP. This integral membrane protein forms a voltage-independent calcium-activated channel with calmodulin-binding subunits.
KCNN2 belongs to the KCNN family of potassium channel genes, and two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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