Thermo Fisher Scientific Ephrin B1/B3 Polyclonal Antibody
Ephrin B1/B3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 사용 가능. 비포스포펩타이드 항원을 기반으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로 세포 부착 및 이동 관련 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic non-phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr330 (N-I-Y-Y-K) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554671 |
Target Information
Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis, indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that affect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development. The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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