Thermo Fisher Scientific SOD3 Polyclonal Antibody
SOD3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에서 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, Affinity chromatography로 정제된 1 mg/mL 액상 제품입니다. PBS buffer에 50% glycerol 포함, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SOD3 (Accession P08294), corresponding to amino acid residues V115–A165 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852285 |
Product Specific Information
Antibody detects endogenous levels of total SOD3.
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and shows increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. The protein localizes to the nucleus and promotes the stability and nuclear accumulation of a transcriptionally active p53 molecule. It phosphorylates Thr18 of p53, reducing its ubiquitination, and may regulate cell proliferation. It also phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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