Thermo Fisher Scientific GPR143 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GPR143. Recombinant protein control fragment (Product #RP-92329). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR143,uniProtId:P51810-1,ncbiNodeId:9606,antigenRange:316-400,antigenLength:404,antigenImageFileName:PA5-51984_GPR143_P51810-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51984_GPR143_P51810-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642166

Product Specific Information

Immunogen sequence: CSLGFQSPRK EIQWESLTTS AAEGAHPSPL MPHENPASGK VSQVGGQTSD EALSMLSEGS DASTIEIHTA SESCNKNEGD PALPT

Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 55%.

Target Information

Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.