Thermo Fisher Scientific GPR143 Polyclonal Antibody
Human GPR143 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 시각 및 피부 멜라닌세포 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPR143. Recombinant protein control fragment (Product #RP-92329) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642166 |
Product Specific Information
Immunogen sequence:
CSLGFQSPRK EIQWESLTTS AAEGAHPSPL MPHENPASGK VSQVGGQTSD EALSMLSEGS DASTIEIHTA SESCNKNEGD PALPT
Ortholog Sequence Identity:
- Mouse: 55%
- Rat: 55%
Target Information
Ocular albinism type 1 protein (GPR143) is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes.
Defects in GPR143 cause ocular albinism type 1 (OA1), also known as Nettleship-Falls type ocular albinism, an X-linked disorder characterized by severe visual impairment, retinal hypopigmentation, and macromelanosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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