
Thermo Fisher Scientific FAT1 Polyclonal Antibody
Human FAT1 단백질을 검출하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며, PBS/glycerol 버퍼에 저장. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human FAT atypical cadherin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636113 |
Product Specific Information
This antibody detects endogenous levels of total FAT1 protein.
Target Information
The FAT1 gene is an ortholog of the Drosophila fat gene, a tumor suppressor essential for controlling cell proliferation during development. The gene product belongs to the cadherin superfamily, characterized by cadherin-type repeats. It contains 34 tandem cadherin-type repeats, five EGF-like repeats, and one laminin A-G domain. FAT1 is highly expressed in fetal epithelia and likely functions as an adhesion molecule and/or signaling receptor, playing roles in developmental processes and cell communication. Transcript variants from alternative splicing or promoter usage exist but are not fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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