Product name: |
Recombinant Human PFKM (C-6His) |
Description: |
Recombinant Human PhosphoFructoKinase, Muscle Type is produced by our Mammalian expression system and the target gene encoding Thr2-Val780 is expressed with a 6His tag at the C-terminus. |
Expression Host: |
Human Cells |
Accession: |
P08237 |
Molecular weight: |
86.1 KDa |
Apparent molecular weight: |
93 KDa, reducing conditions |
Other names: |
6-phosphofructokinase, muscle type; Phosphofructo-1-kinase isozyme A; Phosphofructokinase 1; Phosphohexokinase; PFKM; PFKX |
FORMULATION: |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, 5% Trehalose, pH 6.9. |
Purity: |
Greater than 95% as determined by reducing SDS-PAGE. |
Endotoxin: |
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Storage: |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Delivery condition: |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Background: |
6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. |