Thermo Fisher Scientific NEIL1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NEIL1 protein. Validated for IHC(P) and ICC/IF applications. Supplied as liquid, 0.4 mg/mL, purified by antigen affinity chromatography. Recommended for DNA repair and oxidative damage research.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NEIL1. Recombinant protein control fragment (Product #RP-101323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644599 |
Product Specific Information
Immunogen sequence:
KSKATQLSPE DRVEDALPPS KAPSRTRRAK RDLPKRTATQ RPEGTSLQQD PEAPTVPKKG RRKGRQAASG HCRPRKVKAD IPSLEPE
- Highest antigen sequence identity to orthologs:
- Mouse: 49%
- Rat: 48%
Target Information
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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