Thermo Fisher Scientific Phospho-CD5 (Tyr453) Polyclonal Antibody
CD5 단백질의 Tyr453 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 인간, 마우스, 랫트 반응성 확인. 항원 친화 크로마토그래피 정제, 1 mg/mL 농도, 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human CD5 around the phosphorylation site of Y453 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609693 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein.
It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas.
CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation.
CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes.
In lymph nodes, the main reactivity is observed in T cell areas.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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