Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI16H9), TrueMAB
PD-L1 단백질을 인식하는 Mouse Monoclonal Antibody (Clone OTI16H9). Western Blot에 적합하며, Human 시료에 반응. Affinity chromatography로 정제된 1 mg/mL 액상 시약. PBS/BSA/glycerol buffer에 보존되며, -20°C에서 보관.
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Applications
- Western Blot (WB): 1:500 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI16H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–290 of human CD274 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant on many murine and human cancers and can be up-regulated by IFN-γ stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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