
Thermo Fisher Scientific MBD3 Monoclonal Antibody (106B691)
MBD3 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry, ChIP assay 등에 사용 가능. 인간 MBD3의 215-230 아미노산 서열 기반 합성 펩타이드로 제작. Rat 및 Mouse에서도 반응 예측. 액상 형태, 1.0 mg/mL 농도, 4°C 단기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
| Flow Cytometry (Flow) | 1 µg/million cells | - |
| ChIP assay (ChIP) | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 106B691 |
| Immunogen | Synthetic peptide corresponding to residues C(215) K A F M V T D E D I R K Q E E(230) of human MBD3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_1076608 |
Product Specific Information
This antibody is predicted to react with rat and mouse based on sequence homology.
Suggested positive control: HeLa nuclear extract.
Target Information
Regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. Necessary for centrosome duplication. It functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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