Thermo Fisher Scientific Argonaute 3 Polyclonal Antibody
Rabbit polyclonal antibody against human Argonaute 3 (AGO3). Validated for IHC (Paraffin) and ELISA. Recognizes recombinant AGO3 (251–400 aa). Supplied as liquid, 2.75 mg/mL in PBS with 50% glycerol. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Argonaute-3 protein (251–400 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.75 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2914959 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
AGO3 (protein argonaute-3) is required for RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses translation of complementary mRNAs. AGO3 is proposed to stabilize small RNA derivatives (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and to mediate riRNA-dependent degradation of certain RNA polymerase II-transcribed coding mRNAs by recruiting an mRNA decapping complex involving EDC4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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