Thermo Fisher Scientific Neurensin 2 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence: LLLLLGVAAL TTGYAVPPKL EGIGEGEFLV LDQRAADYNQ ALGTCRLAGT
• Sequence homology:
  • Cow: 86%
  • Dog: 100%
  • Guinea Pig: 83%
  • Horse: 93%
  • Human: 100%
  • Pig: 92%
  • Rabbit: 100%

Target Information

Neurensin-2 (NRSN2) is a 204 amino acid multi-pass membrane protein belonging to the VMP family that may be involved in the transport and maintenance of vesicles. Expressed in the brain, Neurensin-2 localizes to cell bodies of the hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus. It is considered a potential tumor suppressor gene and candidate biomarker for long-term survival in patients with hepatocellular carcinoma (HCC).

The gene encoding Neurensin-2 maps to human chromosome 20, which comprises approximately 2% of the human genome, contains nearly 63 million bases, and encodes over 600 genes. Some of these genes are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome, and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes important for seminal production and potential targets for male contraception.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.