Thermo Fisher Scientific PDX1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Target Information

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression.
Defects in this gene are associated with pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM) and maturity onset diabetes of the young type 4 (MODY4).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.