Thermo Fisher Scientific PSRC1 Polyclonal Antibody
PSRC1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간 및 랫트 시료에 반응하며, 친화 크로마토그래피로 정제됨. PBS 버퍼와 글리세롤에 보관되며 -20°C에서 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PSRC1 (Accession Q6PGN9), corresponding to amino acid residues S275–V325 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852176 |
Product Specific Information
This antibody detects endogenous levels of total PSRC1.
Target Information
PSRC1 is required for normal progression through mitosis. It is essential for proper chromosome congression at the metaphase plate and for the normal rate of chromosomal segregation during anaphase. PSRC1 regulates mitotic spindle dynamics, increases microtubule turnover on metaphase spindles, and contributes to normal tension across sister kinetochores. It recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles and may be involved in p53/TP53-regulated growth suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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