Thermo Fisher Scientific TAS2R14 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TAS2R14. Suitable for WB and IHC applications. Lyophilized, unconjugated form with no preservative. Specific for TAS2R14 involved in bitter taste perception. For research use only.
- 카탈로그번호
- OST00394W-100UL
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous (PubMed)
- Publications: 2 available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 140–180 of human TAS2R14 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TAS2R14.
Target Information
TAS2R14 belongs to the family of candidate taste receptors within the G-protein-coupled receptor superfamily. These proteins are specifically expressed in taste receptor cells of the tongue and palate epithelia. They are organized in genomic clusters linked to loci influencing bitter perception in mice and humans. In functional expression studies, TAS2R14 responds to bitter tastants and maps to the taste receptor gene cluster on chromosome 12p13.
It is a gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and gastrointestinal tract, signaling through PLCB2 and TRPM5, and expressed exclusively in gustducin-positive cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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