Thermo Fisher Scientific RNF14 Polyclonal Antibody
RNF14 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC(P) 응용에 적합합니다. 인간, 마우스, 랫트에 반응하며, Protein A로 정제된 Rabbit IgG 형식입니다. KLH 접합 합성 펩타이드 면역원에서 유래하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific RNF14 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RNF14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the RNF14 gene contains a RING zinc finger motif involved in protein-protein interactions. It interacts with androgen receptor (AR) and may act as a coactivator inducing AR target gene expression in prostate tissue. A dominant negative mutant of this gene inhibits AR-mediated prostate cancer growth. RNF14 also interacts with class III ubiquitin-conjugating enzymes (E2s) and may function as a ubiquitin-ligase (E3) for certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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