Thermo Fisher Scientific RGS17 Polyclonal Antibody
Human RGS17 단백질을 표적으로 하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 분석에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 버퍼에 보관되며 연구용으로 사용됨.
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Thermo Fisher Scientific RGS17 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RGS17. Recombinant protein control fragment (Product #RP-91719). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646519 |
Product Specific Information
Immunogen sequence:
NEGTPAVSQA PGNQRPNNTC CFCWCCCCSC SCLTVRNEER GENAGRPTHT TKMESIQVLE ECQNPTAEEV LSWSQNFDKM MKAPAGRNLF REFLRTEY
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 94%
Target Information
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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