Thermo Fisher Scientific ERI1 Monoclonal Antibody (OTI1B3)
ERI1 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간, 비인간 영장류, 랫트 반응성을 가지며, 액상형으로 제공됩니다. RNA 및 히스톤 mRNA 관련 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B3 |
| Immunogen | Full-length human recombinant protein of ERI1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724263 |
Target Information
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting an essential role in histone mRNA decay after replication.
Requires 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end for efficient RNA degradation.
Also degrades 3'-overhangs of siRNAs in vitro, indicating a possible role in RNA interference regulation.
Binds the 5'-ACCCA-3' sequence present in stem-loop structures and other mRNAs.
Required for 5.8S rRNA 3'-end processing and binds 5.8S ribosomal RNA with high affinity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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