Thermo Fisher Scientific RRAGC Polyclonal Antibody
RRAGC 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, ICC/IF, IP 등에 사용 가능. 사람, 마우스, 원숭이, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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Thermo Fisher Scientific RRAGC Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the sequence of human RagC protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 19 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982552 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. It cycles between an inactive GTP-bound and an active GDP-bound form.
In its active form, RRAGC participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This re-localization is a crucial step in the activation of the TOR signaling cascade by amino acids.
Additional Information
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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