Thermo Fisher Scientific TLX Polyclonal Antibody
TLX 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC에 적합합니다. 인간 시료에 반응하며, 고순도 Affinity Chromatography 정제 제품입니다. PBS 기반 완충액에 보존되어 안정적이며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (IHC) | 5 µg/mL | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human NR2E1 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576373 |
Product Specific Information
Peptide sequence:
MSKPAGSTSR ILDIPCKVCG DRSSGKHYGV YACDGCSGFF KRSIRRNRTY
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
Nuclear receptor TLX (NR2E1) is a NR2 hepatocyte NF4-like receptor involved in anterior brain differentiation, retinal development, and vision. TLX regulates genes such as RAR beta2 and Pax2 during retinal development. Homozygous TLX mutant mice show reduced forebrain development and increased aggression. TLX expression is documented in mouse brain and eye, and ESTs have been isolated from normal human brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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