Thermo Fisher Scientific CA19-9/Sialyl Lewisa (GI Tumor Marker) Monoclonal Antibody (121SLE)
CA19-9/Sialyl Lewis A 단일클론 항체(121SLE)는 인간 GI 종양 마커 연구용으로 최적화된 항체입니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 단일클론 Mouse IgM 형식입니다. 비결합형 액상 제형으로, 고순도 Protein A/G 정제 및 PBS 완충액 보존 상태입니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 121SLE |
| Immunogen | Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Mucin glycoprotein is a Sialyl Lewis A structure synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis A and/or Lewis B blood group antigens.
In normal tissues, sialyl Lewis A antigen is found in ductal epithelium of the breast, kidney, salivary gland, and sweat glands.
Its expression is significantly enhanced in serum and in most tumor cells of gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas.
Preoperative elevated CA19-9 levels in stage I pancreatic carcinoma patients decrease to normal values following surgery.
Serial use of CA19-9 can predict recurrence before radiographic or clinical findings.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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