Thermo Fisher Scientific CDKN2B Monoclonal Antibody (OTI3E4), TrueMAB
인간 CDKN2B 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 Flow Cytometry에 적합. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E4 |
| Immunogen | Full length human recombinant protein of human CDKN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The four known 15-to 19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c and p19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2 and cyclin B-Cdk1.
Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant.
p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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