Thermo Fisher Scientific SLC15A1 Polyclonal Antibody
SLC15A1(PEPT1) 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ELISA에 적합합니다. Protein A로 정제되었으며 1 mg/mL 농도의 액상 형태입니다. 인간 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human PEPT1 aa 350–600/708 (Extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2932477 |
Target Information
In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins.
PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues.
Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential.
PEPT1 is a 708 amino acid protein containing 12 putative membrane-spanning domains and is expressed in Caco-2 cells.
PEPT1 plays important roles in nutritional and pharmacological therapies.
The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, which is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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