Thermo Fisher Scientific CX3CR1 Monoclonal Antibody (10D5)
CX3CR1 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot과 ELISA에 적합. 인간 시료 반응성 확인됨. 액상 형태로 제공되며 PBS buffer에 보존. HIV 관련 연구 및 면역학적 분석에 활용 가능.
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Thermo Fisher Scientific CX3CR1 Monoclonal Antibody (10D5)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10D5 |
| Immunogen | CX3CR1 (AAH28078, 1–36 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDQFPESVTE NFEYDDLAEA CYIGDIVVFG TVFLSI
Target Information
CX3CR1 is one of the chemokine receptors required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28, CMKBRL1, CX3CR1, and RBS11, respectively.
This seven-transmembrane protein acts as the receptor for fractalkine and was renamed CX3CR1. It serves as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractalkine.
CX3CR1 mediates leukocyte migration and adhesion and is expressed in various human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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