Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI1B5), TrueMAB
NAPSA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 분석에 적합. 인간 시료에 반응하며, 동결건조 형태로 제공. 재구성 후 1 mg/mL 농도에서 사용 가능. 암 연구 및 바이오마커 분석에 활용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 64–244 of human NAPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Napsin 1 is an aspartic protease primarily expressed in the lung, and also found in kidney and various metastatic carcinomas. It processes surfactant protein B in pulmonary and renal tissues, but its regulation is altered in carcinogenesis.
Napsin evaluation is useful for identifying and differentiating several cancers, particularly when combined with thyroid transcription factor analysis. It serves as a specific biomarker for carcinoma differentiation and has been linked to pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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