Thermo Fisher Scientific ABCB4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ABCB4 protein. Unconjugated liquid form with 0.1 mg/mL concentration. Suitable for research use in ABC transporter and phospholipid transport studies. Store at 4°C short term or -20°C long term.
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Thermo Fisher Scientific ABCB4 Polyclonal Antibody
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABCB4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637531 |
Product Specific Information
- Immunogen sequence:
HSELMKKEGV YFKLVNMQTS GSQIQSEEFE LNDEKAATRM APNGWKSRLF RHSTQKNLKN SQMCQKSLDV ETDGLEANVP PVS - Highest antigen sequence identity to the following orthologs:
- Mouse: 69%
- Rat: 72%
Target Information
The membrane-associated protein encoded by ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White.
This protein belongs to the MDR/TAP subfamily, which is involved in multidrug resistance and antigen presentation.
ABCB4 encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate.
Its function may involve transport of phospholipids from liver hepatocytes into bile.
Alternative splicing results in several products of undetermined function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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