Thermo Fisher Scientific PSMA1 Polyclonal Antibody
Rabbit 유래의 PSMA1 폴리클로날 항체로 Western blot, IHC, IP 등에 사용 가능. Human PSMA1(213-263 aa) 영역을 면역원으로 제작. 1 mg/mL 액상 형태로 제공되며 4°C 보관. Bovine 및 Orangutan에도 반응 예측.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 213 and 263 of Human Proteasome (Prosome, Macropain) Subunit, Alpha Type, 1 (PSMA1, UniProt ID: P25786-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, antibody predicted to react with Bovine and Orangutan
Target Information
Proteolytic degradation is essential for maintaining appropriate levels of short-lived and regulatory proteins involved in various cellular processes such as metabolism, stress response, antigen presentation, receptor modulation, ion channel regulation, cell cycle, transcription, and signaling.
The ubiquitin-proteasome pathway is the major protein degradation mechanism in eukaryotic cells, involving the 26S proteasome complex (approximately 2.5 MDa), composed of a 20S core and 19S regulatory subunits.
Defects in this pathway are linked to genetic diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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