Thermo Fisher Scientific NR5A1 Polyclonal Antibody
NR5A1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에 적합하며, 다양한 포유류 종에서 높은 예측 반응성을 보임. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 보관 권장.
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- PA130599
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- pk
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Thermo Fisher Scientific NR5A1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of human NR5A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2154046 |
Product Specific Information
- Recommended positive controls: HepG2, human fetal heart, human fetal liver, human fetal lung, human fetal muscle, human heart, human placenta
- Predicted reactivity:
Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Mouse: 79%, Rabbit: 85%, Rat: 92%, Sheep: 85% - Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2), common to nuclear steroid receptors, necessary for interaction with other nuclear receptors, coactivators, and corepressors including SRC-1, GRIP1, CBP, and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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