Thermo Fisher Scientific NDUFS1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NDUFS1 for WB and ICC/IF applications. Validated for high specificity with recombinant antigen. Supplied as liquid form, 0.5 mg/mL, purified by antigen affinity chromatography. Store at 4°C short term or -20°C...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NDUFS1. Recombinant protein control fragment (Product # RP-105323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662747 |
Product Specific Information
Immunogen sequence:
REDWKIIRALS EIAGMTLPYD TLDQVRNRLE EVSPNLVRYD DIEGANYFQQ ANELSKLVNQ QLLADPLVPP QLTIKDFYMT DSISRASQTM AKCVKAV
Highest antigen sequence identity to orthologs:
- Mouse: 93%
- Rat: 91%
Target Information
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I consists of 45 subunits and is located in the mitochondrial inner membrane. It exhibits NADH dehydrogenase and oxidoreductase activities, transferring electrons from NADH to the respiratory chain. The immediate electron acceptor is believed to be ubiquinone. This protein, the largest subunit of complex I, is part of the iron-sulfur fragment and may form part of the active site where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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