Thermo Fisher Scientific ATP8A2 Polyclonal Antibody
ATP8A2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 유세포분석에 적합합니다. Human 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C 권장, 연구용 전용 시약입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 293–322 amino acids from the N-terminal region of human ATP8A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.36 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541917 |
Target Information
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also contributes to vesicle formation and uptake of lipid signaling molecules. The ATP8A2:TMEM30A flippase complex predominantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). It functions in maintaining phospholipid asymmetry in photoreceptor disk and neuronal axon membranes and may participate in vesicle trafficking in neuronal cells. Involved in regulation of neurite outgrowth in synergy with TMEM30A, and required for normal visual and auditory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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