Thermo Fisher Scientific ZRANB2 Polyclonal Antibody
ZRANB2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC에 적합합니다. 인간 시료 반응성이 있으며 Rabbit IgG로 제작되었습니다. 합성 펩타이드 면역원 기반으로 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human ZRANB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609932 |
Product Specific Information
Peptide sequence:
EDKESEGEEE DEDEDLSKYK LDEDEDEDDA DLSKYNLDAS EEEDSNKKKS
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Target Information
Zinc-finger proteins contain DNA-binding domains and perform diverse functions including transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1, or ZIS2, is a 330 amino acid nuclear protein belonging to the ZRANB2 family.
It functions as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts and may interfere with constitutive 5'-splice selection.
ZNF265 contains two RanBP2-type zinc fingers enabling RNA-binding activity. Two isoforms (ZIS-1 and ZIS-2) are expressed due to alternative splicing.
Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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