Thermo Fisher Scientific Calpain 9 Monoclonal Antibody (OTI3G10)
Calpain 9 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 다양한 종(인간, 개, 설치류 등)에 반응하며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G10 |
| Immunogen | Full length human recombinant protein of CAPN9 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722910 |
Target Information
Calpains are a well-conserved family of calcium-dependent cysteine proteases. These proteins are heterodimers composed of an invariant small subunit and variable large subunits. The large subunit includes a cysteine protease domain, and both subunits have calcium-binding domains. Calpains are implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress.
The Calpain 9 protein is predominantly expressed in the stomach and small intestine and may have specialized roles in the digestive tract. It has been associated with gastric cancer, and multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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