Thermo Fisher Scientific SARS-CoV-2 ORF3a Polyclonal Antibody
SARS-CoV-2 ORF3a 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. Western blot, ELISA, IP 등 다양한 응용 가능. 고순도 친화 크로마토그래피 정제. 안정적 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific SARS-CoV-2 ORF3a Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken from a unique amino acid sequence on ORF3a protein (Severe acute respiratory syndrome coronavirus 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ORF3A forms homotetrameric potassium-sensitive ion channels (viroporin) and may modulate virus release.
Up-regulates expression of fibrinogen subunits FGA, FGB, and FGG in host lung epithelial cells.
Induces apoptosis in cell culture.
Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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