Thermo Fisher Scientific AKAP4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AKAP4. Recombinant protein control fragment (Product #RP-92143). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AKAP4,uniProtId:Q5JQC9-1,ncbiNodeId:9606,antigenRange:78-216,antigenLength:854,antigenImageFileName:PA5-54129_AKAP4_Q5JQC9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54129_AKAP4_Q5JQC9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637811

Product Specific Information

Immunogen sequence: EIIVIKDTEK KDQSKTEGSV CLFKQAPSDP VSVLNWLLSD LQKYALGFQH ALSPSTSTCK HKVGDTEGEY HRASSENCYS VYADQVNIDY LMNRPQNLRL EMTAAKNTNN NQSPSAPPAK PPSTQRAVIS PDGECSIDD

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.

Target Information

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.