Thermo Fisher Scientific AKAP4 Polyclonal Antibody
Human AKAP4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석으로 사용 가능. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적. 정자 운동성과 신호전달 연구에 적합.
- 카탈로그번호
- PA554129
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AKAP4 (Product #RP-92143) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2637811 |
Product Specific Information
Immunogen sequence:
EIIVIKDTEK KDQSKTEGSV CLFKQAPSDP VSVLNWLLSD LQKYALGFQH ALSPSTSTCK HKVGDTEGEY HRASSENCYS VYADQVNIDY LMNRPQNLRL EMTAAKNTNN NQSPSAPPAK PPSTQRAVIS PDGECSIDD
- Highest antigen sequence identity to orthologs: Mouse - 81%, Rat - 82%
Target Information
A-kinase anchor proteins (AKAPs) are a diverse group of proteins that bind to the regulatory subunit of protein kinase A (PKA), confining the holoenzyme to specific cellular locations.
AKAP4 (also known as hAKAP82) is a major sperm fibrous sheath protein localized along the entire flagellum of human sperm. It is implicated in sperm motility and signal transduction regulation.
AKAP4 has also been suggested as a potential biomarker for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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