Thermo Fisher Scientific MKK7 Polyclonal Antibody
MKK7 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합합니다. 1 mg/mL 농도의 액상 형태이며 4°C에서 보관합니다. 인체 MKK7의 1–50번 잔기 구간을 면역원으로 사용했습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1–50 of human Mitogen-Activated Protein Kinase Kinase 7 (MKK7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat.
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2, and is itself phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified, but only one variant is fully supported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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