Thermo Fisher Scientific Calpain 9 Polyclonal Antibody
Human Calpain 9 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500–1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 위장관 특이적 발현 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Calpain 9 (Product #RP-91742) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639248 |
Product Specific Information
Immunogen sequence:
PGEYILIPST FEPHQEADFC LRIFSEKKAI TRDMDGNVDI DLPEPPKPTP PDQETEEEQR FRALFEQVAG EDMEVTAEEL EYVLNAVLQK KKDIKFKKLS
Sequence identity:
- Mouse: 82%
- Rat: 80%
Target Information
Calpains are a family of calcium-dependent cysteine proteases composed of an invariant small subunit and variable large subunits. The large subunit contains a cysteine protease domain, and both subunits include calcium-binding domains. Calpain activation is triggered by calcium influx and oxidative stress, implicating them in neurodegenerative processes.
Calpain 9 is predominantly expressed in the stomach and small intestine, suggesting specialized digestive functions and potential association with gastric cancer. Multiple alternatively spliced transcript variants exist for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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