Thermo Fisher Scientific QDPR Polyclonal Antibody
Thermo Fisher Scientific의 QDPR Polyclonal Antibody는 인간 QDPR 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 PBS/glycerol 완충액 형태로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human QDPR. Recombinant protein control fragment (Product # RP-103971) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646182 |
Product Specific Information
Immunogen sequence:
WVASVDVVEN EEASASIIVK MTDSFTEQAD QVTAEVGKLL GEEKVDAILC VAGGWAGGNA KSKSLFKNCD LMWKQSIWTS TISSHLATKH
Sequence identity:
- Mouse: 91%
- Rat: 96%
Target Information
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems.
Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations.
Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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