
Thermo Fisher Scientific LIMS1 Polyclonal Antibody
LIMS1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 반응성. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적 액상 형태로 연구용 적합.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LIMS1, amino acids 101–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is an adaptor protein containing five LIM domains (double zinc fingers). It is likely involved in integrin signaling through LIM domain-mediated interaction with integrin-linked kinase found in focal adhesion plaques. It may act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which participates in growth factor receptor kinase signaling pathways. Localization to the periphery of spreading cells suggests a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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